O mně
(člen oddělení od roku 2019)
Jsem filosof vědy a specificky se zaměřuji se na koncepční otázky v imunologii. V současné době se mé výzkumné zájmy týkají konceptu tolerance onemocnění a interakcí mezi imunitním systémem a jinými fyziologickými systémy. Provozuji platformu Prague Meetings in Philosophy of Science pro pořádání akcí o biomedicínském výzkumu a filosofii vědy. Za svůj výzkum jsem v roce 2023 obdržel cenu Akademie věd ČR za vynikající výsledky a v roce 2024 Prémii Otto Wichterleho. Ve své disertační práci obhájené v roce 2021 jsem se zabýval povahou vědeckého modelování v kontextu koncepčního a experimentálního výzkumu v nádorové imunologii. Mezi mé další výzkumné zájmy patří také tradičnější filosofické debaty o (biologických) mechanismech, vědeckém porozumění, naturalismu a scientismu.
Jsem zastáncem filozofie, která je relevantní a úzce spojená s vědeckou praxí. Na toto téma jsem také odpovídal v různých médiích, např.: vědavýzkum.cz, ČRo Plus, Filosofický podcast. Jak to funguje v praxi, se také dozvíte z mých úvodního vystoupení na akcích, které nedávno uspořádalo naše oddělení:
Základní oblasti výzkumu: filozofie vědy, filozofie biologie, filozofie medicíny.
CV
Vzdělání
- 2016 - 2021 PhD v oboru Filosofie, Ústav filosofie a religionistiky, Filozofická fakulta UK
- Školitelé: Ladislav Kvasz, Roman Frigg (London School of Economics)
- Oponenti: Sabina Leonelli (Exeter), Michael Weisberg (Minnesota), Marshall Abrams (Alabama)
- 2014-2016 Mgr. v oboru Německá a francouzská filosofie, Fakulta humanitních studií UK
- 2011-2014 Bc. v oboru Studium humanitní vzdělanosti, Fakulta humanitních studií UK
Výzkumné pobyty
- 2020 (zrušeno kvůli COVID-19) EPSA Fellow at the ImmunoConcEpT, CNRS UMR 5164, University of Bordeaux
- 2019 (October - December) Research visitor at the ImmunoConcEpT, CNRS UMR 5164, University of Bordeaux, host: Thomas Pradeu
- 2018 (August - November) Research visitor at the Centre for Philosophy of Social Science ('TINT'), University of Helsinki, host: Uskali Mäki
- 2017 (September - December) Research visitor at the Centre for Philosophy of Natural and Social Science (CPNSS), London School of Economics, host: Roman Frigg
Grantové projekty
- 2024-2026 Immunity and biological resilience, Czech Science Foundation (GA CR 24-11861S) (PI)
- 2019–2021 Simplifying assumptions and noncausal explanations, Czech Science Foundation (GA CR 19-04236S) (co-principal investigator with Lukas Zamecnik from Palacky University Olomouc)
- 2017–2019 Philosophical aspects of scientific models, Charles University Grant Agency (project no. 66217) (PI)
- 2017–2018 Principles of naturalizing philosophy of science, Internal Grant of the Faculty of Arts, Charles University (FF/VG/2017/3) (PI)
Stipendia
- 2019 EPSA Fellowship (visiting ImmunoConcEpT)
- 2019 French government scholarship (visiting ImmunoConcEpT)
- 2018 Scholarship from the "Hlavka foundation"
- 2018 EDUFI Fellowship (visiting Helsinki)
- 2017 Anglo-Czech Education Fund (visiting LSE)
Organizace
- 2022, October 24-25, Prague International workshop "Immunology Meets Philosophy"
- 2020, October 28-30, Prague Conference: "Conceptual and Methodological Aspects of Biomedical Research"
- 2019, August 5-10, Prague Congress Secretary and member of the LOC for CLMPST 2019
- 2019, June 12-14, Prague International workshop "Idealization Across the Sciences"
- 2018, May 28-29, Prague International workshop "Representation in Science"
- 2017, May 18-19, Prague International workshop "Perspectives on Explanation"
Recenzní posudky pro
Knižní nakladatelství
- Cambridge University Press
- Academia
Odborné časopisy
- European Journal of Immunology
- Biology & Philosophy
- European Journal for Philosophy of Science
- Philosophy of Science
- Studies in History and Philosophy of Science
- History and Philosophy of the Life Sciences
- Journal for General Philosophy of Science
- Perspectives in Biology and Medicine
- Perspectives on Science
- Acta Analytica
- Filozofia
- Filosofie dnes
Členství
- European Philosophy of Science Association (EPSA): student representative for the steerring committee (2019-2021)
- East European Network for Philosophy of Science (EENPS): member of the steering committee (2020-2024)
- Philosophy of Science Association (PSA)
- International Society of the History, Philosophy, and Social Studies of Biology (ISHPSSB)
- Society for Philosophy of Science in Practice (SPSP): member of the editorial board of the newsletter
- Philosophy in Biology and Medicine Network (PhilInBioMed /PIBM)
Publikace
2024
- 1 paper(s) currently under review (Studies in History and Philosophy of Science (IF: 1.379))
- How technical advances changed the concept of antibodies (with Bartlomiej Swiatczak & Gregor Greslehner). Forthcoming in Immunological Reviews.
- Simplifying Assumptions in Noncausal Explanations (in Czech) (with Lukáš Zámečník), forthcoming in Teorie vědy/Theory of Science, https://doi.org/10.46938/tv.2024.615
2023
- On the relationship between asymptomatic infections and diseases, Philosophy of Medicine 4 (1), 1-12, https://doi.org/10.5195/pom.2023.171
- Understanding immunity: an alternative framework beyond defense and strength (with Gregor Greslehner), Biology & Philosophy 38 (1), (IF: 1.795), https://doi.org/10.1007/s10539-023-09893-2
2022
- Towards an extended view of immunity: a philosophical perspective (with Gregor Greslehner), Anaesthesia Critical Care & Pain Medicine 41 (6), 101156 (IF: 7.025), https://doi.org/10.1016/j.accpm.2022.101156
- A Complementary Account of Scientific Modeling: Modeling Mechanisms in Cancer Immunology, forthcoming in British Journal for the Philosophy of Science (IF: 3.978), https://doi.org/10.1086/721530
- Revisiting abstraction and idealization: How not to criticize mechanistic explanation in molecular biology, European Journal for Philosophy of Science 12 (1), 1-21 (IF: 1.753), https://doi.org/10.1007/s13194-022-00453-1
2021
- Assessing the quality of evidence from epidemiological agent-based models for the COVID-19 pandemic (with Mariusz Maziarz), History and Philosophy of the Life Sciences 43 (1), 1-4 (IF: 1.205) (https://doi.org/10.1007/s40656-020-00357-4)
2020
- Agent-based modeling for SARS-CoV-2 epidemic prediction and intervention assessment. A methodological appraisal (with Mariusz Maziarz), Journal of Evaluation in Clinical Practice 26 (5), 1352-1360 (IF: 1.68) (https://onlinelibrary.wiley.com/doi/full/10.1111/jep.13459)
2019
- Conceptual Analysis in the Philosophy of Science. Balkan Journal of Philosophy 11 (2), 107-124
2017
- Vědecký realismus jako kultivace ducha, Filozofia 72 (5), 381-391
- Selektivní realismus a kalorická teorie tepla, Filosofický časopis 65 (1), 77-95.
Editorial work
- 2019-2021, Idealization, Representation, and Explanation Across the Sciences (with Elay Shech and Melissa Jacquart), special issue of Studies in History and Philosophy of Science (IF: 1.21)
Reviews and reports
- Perspectives on Explanation, 18-19 May, The Reasoner 11 (6), 30-31, 2017.
- Axel Gelfert: How to do science with models: A philosophical primer, Organon F 24 (4), 546-552, 2017.
Prezentace a přednášky
2023
- “Let's talk about immunology: the intricacies of metaphorical language”, International Society for the History Philosophy and Social Studies of Biology biennial meeting (ISHPSSB 2023), Toronto (Canada), 9-15 July 2023 (online)
- “What immunology tells us about the nature of mechanistic modelling”, XI. Ernst Mach Workshop: Causation – Structure, Models and Realism, Prague (CZ), 23-24 May 2023
2022
- “Immunity in health and disease: a clash of frameworks”, 4th Conference of the East European Network for Philosophy of Science, Tartu (Estonia), 17-19 August 2022 (online)
- “Doing without Model Systems and Descriptions: A Cognitive Artifact View of Models”, Prague – Valencia Workshop on Analytic Philosophy, Prague (CZ), 22-23 September 2022
- “The role of assumptions in modeling cancer” (invited talk), Emerging models in cancer research: 3rd Thematic day at Centre de Recherche en Cancérologie de Lyon (CRLC), 14 January 2022 (online)
2021
- “Epistemic roles of similarity considerations in mouse models of cancer”, 8th Biennial Conference of the European Philosophy of Science Association (EPSA21), Turin (Italy), 15-18 September 2021 (online?)
- “Epistemic roles of similarity considerations in mouse models of cancer”, British Society for Philosophy of Science Annual Conference (BSPS2021), Kent (UK), 7-9 July 2021 (online)
- “How to think about the immune system in times of COVID-19 and beyond: why stronger isn’t always better and other misleading metaphors”, 9th Philosophy of Medicine Roundtable, Michigan State University (USA), 27-30 June 2021 (online)
- “Modeling in Biomedicine: Extending the notion of models”, Third conference of the East European Network for Philosophy of Science (EENPS 2021), Belgrade (Serbia), June 9-11 2021 (online)
- “How to think about the immune system in times of COVID-19 and beyond: why stronger isn’t always better and other misleading metaphors”, Philosophical Perspectives on Covid-19, 10-13 May 2021 (online)
- “Building Mechanistic Models in Cancer Immunology: Towards a Complementary Account of Modeling” (poster), 27th Biennial Meeting of the Philosophy of Science Association (PSA2021), Jan. 22, Jan. 29, and Feb. 5, 2021 (online)
2020
•“Modeling in Cancer Immunology: A Complementary Account”, Bordeaux-Sydney Workshop on Philosophy of Biology and Biomedicine, 23-24 November 2020
• “Are ABM epidemic models the models of actual mechanisms?” (jointly with M. Maziarz), Jagiellonian University, 5 May 2020
• "Representing cancer in humans: Reviving the similarity account of scientific representation", 2nd SURe Workshop, Atlanta (USA), 12.-13.3.2020
2019
• "Theoretical models as abstract objects?", 4th POND Conference, Barcelona (Spain), 26-27 September 2019
• "Revisiting abstraction and idealization in molecular biology", 7th Biennial Conference of the European Philosophy of Science Association (EPSA19), Geneva (Switzerland), 6.-9.9.2019
· "Revisiting abstraction and idealization in molecular biology", British Society for Philosophy of Science Annual Conference (BSPS 2019), Durham (UK), 17.-19.7.2019
· "The case of mechanistic explanation in molecular biology: abstraction or idealization?“, International Society for the History Philosophy and Social Studies of Biology biennial meeting (ISHPSSB 2019), Oslo (Norway), 7.-12.7.2019
· "On Abstraction and Idealization in Molecular Biology", workshop Idealization Across the Sciences, Prague (Czech Republic), 12.-14.6.2019
· "Idealization and understanding with diagrammatic biological models“, Third International Conference of the German Society for Philosophy of Science (GWP2019), Cologne (Germany), 25.-27.2.2019
2018
· "Scientific understanding and the facticity condition", IX Conference of the Spanish Society for Logic, Methodology and Philosophy of Science (SLMFCE), Madrid (Spain), 13.-16.11.2018
· "A case for factive scientific understanding" (poster), 26th Biennial Meeting of the Philosophy of Science Association (PSA2018), Seattle, WA (USA), 1.-4.11.2018
· "Mechanistic explanation in agent-based modeling", Joint European Network for the Philosophy of the Social Sciences and Philosophy of Social Science Roundtable Conference, Hannover (Germany), 30.8.-1.9.2018
· "There is no (special) problem of ontology of theoretical models", Fourth Annual Conference of the Society for Metaphysics of Science (SMS4), Milan (Italy), 22.-24.8.2018
· "Similarity in practice", Seventh Biennial Conference of the Society for Philosophy of Science in Practice (SPSP7), Ghent (Belgium), 29.6.-2.7.2018
· "Scientific representation: Resituating the similarity account", Second conference of the East European Network for Philosophy of Science (EENPS 2018), Bratislava (Slovakia), 20.6.-22.6.2018
· "Mechanistic explanation in agent-based modeling" (poster), 11th MuST conference in Philosophy of Science: Models of Explanation, Turin (Italy), 11.6.-13.6.2018
· "Similarity judgments and scientific representation", Representation in Science, Prague (Czech Republic), 28.-29.5.2018
· "Factive understanding with model sketches", Explanation and Understanding, Ghent (Belgium), 23.-25.5.2018
· "Applying pretense to scientific models. Its merits and limits" (invited), XIII. Prague Interpretation Colloqium, Prague (Czech Republic), 23.-25.4.2018
· "Minimal models, representation, and explanation", Models and Simulations 8, Columbia, SC (USA), 15.-17.3.2018
2017
· "Pluralism and minimal models" (poster), What to make of highly unrealistic models?, Helsinki (Finland), 12.-13.10.2017
· "Against the direct fiction view of scientific models“, Sixth Biennial Conference of the European Philosophy of Science Association 2017, Exeter (United Kingdom), 6.-9.9.2017
· "Against the direct fiction view of scientific models“, Ninth European Congress of Analytic Philosophy, Munich (Germany), 21.-26.8.2017
· "Conceptual analysis in philosophy of science", Triennial Conference of the Italian Society for Logic and Philosophy of Science, Bologna (Italy), 20.-23.6.2017
· "Modifying the fiction view of scientific models“, Fifth Annual Meeting of the Nordic Network for Philosophy of Science, Copenhagen (Denmark), 20.-21.4.2017
· "Why the fiction view of scientific models is not your enemy“, Scientific contents: Fictions or abstract objects?, Santiago de Compostela (Spain), 26.-27.1.2017
2016
· "Naturalized philosophy of science: Two accounts of the method of conceptual analysis”, Third Lisbon International Conference on Philosophy of Science, Lisbon (Portugal), 14.-16.12.2016
· "Cesta k naturalizované teorii vědy” (The road to naturalized theory of science), 4th Hradec philosophical days, Hradec Králové (Czech Republic), 6.-7.10.2016
· "Otázka dedukce a pravdy u vědeckých modelů” (The question of deduction and truth in scientific models), XX. Czech-Slovak symposium on analytical philosophy, Prague (Czech Republic), 14.-16.9.2016
· "Science and scientism“, The Inaugural Conference of the East European Network for Philosophy of Science (EENPS 2016), Sofia (Bulgaria), 24.-26.6.2016
Probíhající práce
V současné době pracuji na několika projektech:
- Reprezentace rakoviny pomocí humanizovaných zvířecích modelů ve výzkumu imunoterapie rakoviny
- Klíčové imunologické pojmy a význam vědecké komunikace
- Tolerance v imunologii
- Nemoc: debata o kritériích, lékařské praxi a biologickém výzkumu
- Pojem protilátek a jak se vyvíjel
